In Vivo Assessment of Clobetasol Propionate-Loaded Lecithin-Chitosan Nanoparticles for Skin Delivery

In Vivo Assessment of Clobetasol Propionate-Loaded Lecithin-Chitosan Nanoparticles for Skin Delivery

The aim of this work was to assess in vivo the anti-inflammatory efficacy and tolerability of clobetasol propionate (CP) loaded lecithin/chitosan nanoparticles incorporated into chitosan gel for topical application (CP 0.005%). As a comparison, a commercial cream (CP 0.05% w/w), and a sodium deoxych...

Full description

Bibliographic Details
Main Authors: Taner Şenyiğit, Fabio Sonvico, Alessandra Rossi, Işıl Tekmen, Patrizia Santi, Paolo Colombo, Sara Nicoli, Özgen Özer
Format: Article
Language:English
Published: MDPI AG 2016-12-01
Series:International Journal of Molecular Sciences
Subjects:
topical glucocorticoids
clobetasol propionate
nanoparticles
anti-inflammatory activity
transepidermal water loss
skin irritation
lecithin
chitosan
Online Access:http://www.mdpi.com/1422-0067/18/1/32

Internet

http://www.mdpi.com/1422-0067/18/1/32

Similar Items