Clinical factors associated with circulating tumor DNA (ctDNA) in primary breast cancer

Clinical factors associated with circulating tumor DNA (ctDNA) in primary breast cancer

Noninvasive circulating tumor DNA (ctDNA) can be used to predict breast cancer recurrence and prognosis. In this study, we detected 226 and 114 somatic variants in tumor DNA from 70 primary breast cancer (PBC) patients (98.59%) and ctDNA from 48 patients (67.61%), respectively. Gene frequencies of t...

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Bibliographic Details
Main Authors: Yidong Zhou, Yaping Xu, Yuhua Gong, Yanyan Zhang, Yaping Lu, Changjun Wang, Ru Yao, Peng Li, Yanfang Guan, Jiayin Wang, Xuefeng Xia, Ling Yang, Xin Yi, Qiang Sun
Format: Article
Language:English
Published: Wiley 2019-05-01
Series:Molecular Oncology
Subjects:
circulating cell‐free DNA
clinical factors
concordance
next‐generation sequencing
primary breast cancer
Online Access:https://doi.org/10.1002/1878-0261.12456

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