Troubleshooting Guide to Expressing Intrinsically Disordered Proteins for Use in NMR Experiments

Intrinsically disordered proteins (IDPs) represent a structural class of proteins that do not have a well-defined, 3D fold in solution, and often have little secondary structure. To characterize their function and molecular mechanism, it is helpful to examine their structure using nuclear magnetic r...

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Bibliographic Details
Main Author: Steffen P. Graether
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Molecular Biosciences
Subjects:
NMR
Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2018.00118/full