Paternal germ line aging: DNA methylation age prediction from human sperm

Paternal germ line aging: DNA methylation age prediction from human sperm

Abstract Background The relationship between aging and epigenetic profiles has been highlighted in many recent studies. Models using somatic cell methylomes to predict age have been successfully constructed. However, gamete aging is quite distinct and as such age prediction using sperm methylomes is...

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Bibliographic Details
Main Authors: Timothy G. Jenkins, Kenneth I. Aston, Bradley Cairns, Andrew Smith, Douglas T. Carrell
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Genomics
Subjects:
Sperm epigenetics
Aging
DNA methylation
Aging calculator
Online Access:http://link.springer.com/article/10.1186/s12864-018-5153-4

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