A network of autism linked genes stabilizes two pools of synaptic GABAA receptors

A network of autism linked genes stabilizes two pools of synaptic GABAA receptors

Changing receptor abundance at synapses is an important mechanism for regulating synaptic strength. Synapses contain two pools of receptors, immobilized and diffusing receptors, both of which are confined to post-synaptic elements. Here we show that immobile and diffusing GABAA receptors are stabili...

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Bibliographic Details
Main Authors: Xia-Jing Tong, Zhitao Hu, Yu Liu, Dorian Anderson, Joshua M Kaplan
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-11-01
Series:eLife
Subjects:
autism
synaptic transmission
GABA-A receptors
CASK
neurexin
neuroligin
Online Access:https://elifesciences.org/articles/09648

Internet

https://elifesciences.org/articles/09648

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