Allopregnanolone in premenstrual dysphoric disorder (PMDD): Evidence for dysregulated sensitivity to GABA-A receptor modulating neuroactive steroids across the menstrual cycle

Allopregnanolone in premenstrual dysphoric disorder (PMDD): Evidence for dysregulated sensitivity to GABA-A receptor modulating neuroactive steroids across the menstrual cycle

Premenstrual dysphoric disorder (PMDD) is a severe mood disorder with core symptoms (affective lability, irritability, depressed mood, anxiety) and increased sensitivity to stress occurring in the luteal phase of the menstrual cycle. PMDD can be conceptualized as a disorder of suboptimal sensitivity...

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Bibliographic Details
Main Authors: Liisa Hantsoo, C. Neill Epperson
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Neurobiology of Stress
Subjects:
Menstrual cycle
Premenstrual dysphoric disorder
Premenstrual syndrome
Allopregnanolone
Progesterone
Women's health
Online Access:http://www.sciencedirect.com/science/article/pii/S2352289520300035

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http://www.sciencedirect.com/science/article/pii/S2352289520300035

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