Optogenetic excitation of cholinergic inputs to hippocampus primes future contextual fear associations

Abstract Learning about context is essential for appropriate behavioral strategies, but important contingencies may not arise during initial learning. A variant of contextual fear conditioning, context pre-exposure facilitation, allows us to directly test the relationship between novelty-induced ace...

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Bibliographic Details
Main Authors: Sarah Hersman, Jesse Cushman, Noah Lemelson, Kate Wassum, Shahrdad Lotfipour, Michael S. Fanselow
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02542-1

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