miR-541 Contributes to Microcystin-LR-Induced Reproductive Toxicity through Regulating the Expression of p15 in Mice

miR-541 Contributes to Microcystin-LR-Induced Reproductive Toxicity through Regulating the Expression of p15 in Mice

Microcystin-leucine arginine (MC-LR) is a harmful cyanotoxin produced by cyanobacteria. MC-LR can exert endocrine-disrupting activities in many organisms. We have previously demonstrated that MC-LR exerts both acute and chronic reproductive toxicity in male mice, resulting in a decline in sperm qual...

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Bibliographic Details
Main Authors: Xiannan Meng, Ling Zhang, Xiang Chen, Zou Xiang, Dongmei Li, Xiaodong Han
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Toxins
Subjects:
MC-LR
miR-541
p15
male reproduction
apoptosis
Online Access:http://www.mdpi.com/2072-6651/8/9/260

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