Recent Developments in Data Independent Acquisition (DIA) Mass Spectrometry: Application of Quantitative Analysis of the Brain Proteome

Recent Developments in Data Independent Acquisition (DIA) Mass Spectrometry: Application of Quantitative Analysis of the Brain Proteome

Mass spectrometry is the driving force behind current brain proteome analysis. In a typical proteomics approach, a protein isolate is digested into tryptic peptides and then analyzed by liquid chromatography–mass spectrometry. The recent advancements in data independent acquisition (DIA) mass spectr...

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Bibliographic Details
Main Authors: Ka Wan Li, Miguel A. Gonzalez-Lozano, Frank Koopmans, August B. Smit
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Molecular Neuroscience
Subjects:
proteomics
neuroscience
brain
synapse
LC-MS
quantitative analyses
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2020.564446/full

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