Development of a multiplex methylation-specific PCR as candidate triage test for women with an HPV-positive cervical scrape

Development of a multiplex methylation-specific PCR as candidate triage test for women with an HPV-positive cervical scrape

<p>Abstract</p> <p>Background</p> <p>Quantitative methylation-specific PCR (qMSP) analysis for determining the methylation status of (candidate) tumor suppressor genes has potential as objective and valuable test to triage high-risk human papillomavirus (hrHPV) positive...

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Bibliographic Details
Main Authors: Snellenberg Suzanne, Strooper Lise MA, Hesselink Albertus T, Meijer Chris JLM, Snijders Peter JF, Heideman Daniëlle AM, Steenbergen Renske DM
Format: Article
Language:English
Published: BMC 2012-11-01
Series:BMC Cancer
Subjects:
Cervical cancer
HPV testing
DNA methylation
Promoter
CADM1
MAL
hsa-miR-124-2
Multiplex qMSP
Primer/probe design
7500Fast ABI system
Online Access:http://www.biomedcentral.com/1471-2407/12/551

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