Triterpenoids from Ocimum labiatum Activates Latent HIV-1 Expression In Vitro: Potential for Use in Adjuvant Therapy

Triterpenoids from Ocimum labiatum Activates Latent HIV-1 Expression In Vitro: Potential for Use in Adjuvant Therapy

Latent HIV reservoirs in infected individuals prevent current treatment from eradicating infection. Treatment strategies against latency involve adjuvants for viral reactivation which exposes viral particles to antiretroviral drugs. In this study, the effect of novel triterpenoids isolated from Ocim...

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Bibliographic Details
Main Authors: Petrina Kapewangolo, Justin J. Omolo, Pascaline Fonteh, Martha Kandawa-Schulz, Debra Meyer
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Molecules
Subjects:
Ocimum labiatum
novel triterpenoids
latent HIV-1
HIV-1 eradication
histone deacetylase
protein kinase C
cytokines
Online Access:https://www.mdpi.com/1420-3049/22/10/1703

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