Physicochemical characteristics of structurally determined metabolite-protein and drug-protein binding events with respect to binding specificity.

To better understand and ultimately predict both the metabolic activities as well as the signaling functions of metabolites, a detailed understanding of the physical interactions of metabolites with proteins is highly desirable. Focusing in particular on protein binding specificity vs. promiscuity,...

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Bibliographic Details
Main Authors: Paula eKorkuć, Dirk eWalther
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmolb.2015.00051/full