Pulmonary Procoagulant and Innate Immune Responses in Critically Ill COVID-19 Patients
RationaleSystemic activation of procoagulant and inflammatory mechanisms has been implicated in the pathogenesis of COVID-19. Knowledge of activation of these host response pathways in the lung compartment of COVID-19 patients is limited.ObjectivesTo evaluate local and systemic activation of coagula...
Main Authors: | Esther J. Nossent, Alex R. Schuurman, Tom D.Y. Reijnders, Anno Saris, Ilse Jongerius, Siebe G. Blok, Heder de Vries, JanWillem Duitman, Anton Vonk Noordegraaf, Lilian J. Meijboom, René Lutter, Leo Heunks, Harm Jan Bogaard, Tom van der Poll |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-05-01
|
Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2021.664209/full |
Similar Items
-
Immune Checkpoints as Promising Targets for the Treatment of Idiopathic Pulmonary Fibrosis?
by: JanWillem Duitman, et al.
Published: (2019-09-01) -
Is idiopathic pulmonary fibrosis a cancer-like disease? Transcriptome analysis to fuel the debate
by: C. Arnold Spek, et al.
Published: (2019-02-01) -
Pulmonary hypertension
by: Anton Vonk Noordegraaf, et al.
Published: (2016-03-01) -
Pulmonary arterial hypertension preceding idiopathic pulmonary fibrosis in a BMPR2 mutation positive patient
by: Aniek J. Raamsteeboers, et al.
Published: (2014-03-01) -
Plasmin reduces fibronectin deposition by mesangial cells in a protease-activated receptor-1 independent manner
by: Maaike Waasdorp, et al.
Published: (2017-07-01)