SM934 treated lupus-prone NZB × NZW F1 mice by enhancing macrophage interleukin-10 production and suppressing pathogenic T cell development.

SM934 treated lupus-prone NZB × NZW F1 mice by enhancing macrophage interleukin-10 production and suppressing pathogenic T cell development.

<h4>Background</h4>Artemisinin and its derivatives were reported to possess strong regulatory effects on inflammation and autoimmune diseases. This study was designed to examine the therapeutic effects and underlying mechanisms of SM934, a water-soluble artemisinin analogue, on lupus-pro...

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Main Authors: Li-Fei Hou, Shi-Jun He, Xin Li, Chun-Ping Wan, Yang Yang, Xiao-Hui Zhang, Pei-Lan He, Yu Zhou, Feng-Hua Zhu, Yi-Fu Yang, Ying Li, Wei Tang, Jian-Ping Zuo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22389703/pdf/?tool=EBI

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