Cell aggregation enhances bone formation by human mesenchymal stromal cells

he amount of bone generated using current tissue engineering approaches is insufficient for many clinical applications. Previous in vitro studies suggest that culturing cells as 3D aggregates can enhance their osteogenic potential, but the effect on bone formation in vivo is unknown. Here, we use ag...

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Bibliographic Details
Main Authors: A Chatterjea, VLS LaPointe, A Barradas, H Garritsen, H Yuan, A Renard, CA van Blitterswijk, J de Boer
Format: Article
Language:English
Published: AO Research Institute Davos 2017-02-01
Series:European Cells & Materials
Subjects:
Online Access:http://www.ecmjournal.org/papers/vol033/pdf/v033a09.pdf