Dynamics of antibiotic resistant Mycobacterium tuberculosis during long-term infection and antibiotic treatment.

For an infecting bacterium the human body provides several potential ecological niches with both internally (e.g. host immunity) and externally (e.g. antibiotic use) imposed growth restrictions that are expected to drive adaptive evolution in the bacterium, including the development of antibiotic re...

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Bibliographic Details
Main Authors: Solomon H Mariam, Jim Werngren, Joakim Aronsson, Sven Hoffner, Dan I Andersson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3116863?pdf=render

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