ErbB1-dependent signalling and vesicular trafficking in primary afferent nociceptors associated with hypersensitivity in neuropathic pain

Effective analgesic treatment for neuropathic pain remains an unmet need, so previous evidence that epidermal growth factor receptor inhibitors (EGFRIs) provide unexpected rapid pain relief in a clinical setting points to a novel therapeutic opportunity. The present study utilises rodent models to a...

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Bibliographic Details
Main Authors: Rory Mitchell, Marta Mikolajczak, Christian Kersten, Sue Fleetwood-Walker
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Neurobiology of Disease
Subjects:
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Online Access:http://www.sciencedirect.com/science/article/pii/S0969996120302369