Coenzyme Q10 Ameliorates Pancreatic Fibrosis via the ROS-Triggered mTOR Signaling Pathway
Aim. Pancreatic stellate cells (PSCs) play a pivotal role in pancreatic fibrosis. Any remedies that inhibit the activation of PSCs can be potential candidates for therapeutic strategies in pancreatic fibrosis-related pancreatic ductal adenocarcinoma (PDAC) and chronic pancreatitis (CP). Our study is...
Main Authors: | Ran Xue, Jianxin Wang, Lixin Yang, Xinjuan Liu, Yan Gao, Yanhua Pang, Yanbin Wang, Jianyu Hao |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2019-01-01
|
Series: | Oxidative Medicine and Cellular Longevity |
Online Access: | http://dx.doi.org/10.1155/2019/8039694 |
Similar Items
-
Mitofusin2 Induces Cell Autophagy of Pancreatic Cancer through Inhibiting the PI3K/Akt/mTOR Signaling Pathway
by: Ran Xue, et al.
Published: (2018-01-01) -
Coenzyme Q10 Inhibits the Aging of Mesenchymal Stem Cells Induced by D-Galactose through Akt/mTOR Signaling
by: Dayong Zhang, et al.
Published: (2015-01-01) -
Rapamycin ameliorates kidney fibrosis by inhibiting the activation of mTOR signaling in interstitial macrophages and myofibroblasts.
by: Guochun Chen, et al.
Published: (2012-01-01) -
Chaihu Guizhi Ganjiang Decoction Ameliorates Pancreatic Fibrosis via JNK/mTOR Signaling Pathway
by: Lihua Cui, et al.
Published: (2021-06-01) -
mTOR Overactivation and Compromised Autophagy in the Pathogenesis of Pulmonary Fibrosis.
by: Yao-Song Gui, et al.
Published: (2015-01-01)