Effects of naturally-arising HIV Nef mutations on cytotoxic T lymphocyte recognition and Nef's functionality in primary macrophages

Effects of naturally-arising HIV Nef mutations on cytotoxic T lymphocyte recognition and Nef's functionality in primary macrophages

<p>Abstract</p> <p>Background</p> <p>Although HIV can infect several cellular subsets, such as CD4<sup>+ </sup>T lymphocytes and macrophages, it remains unclear whether an HIV infection in macrophages supports cytotoxic T lymphocyte (CTL) escape. Here, we te...

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Bibliographic Details
Main Authors: Suzu Shinya, Hassan Ranya, Hasan Zafrul, Mwimanzi Philip, Takiguchi Masafumi, Ueno Takamasa
Format: Article
Language:English
Published: BMC 2011-06-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/8/1/50

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