Engineering an Antibody V Gene-Selective Vaccine

Engineering an Antibody V Gene-Selective Vaccine

The ligand-binding surface of the B cell receptor (BCR) is formed by encoded and non-encoded antigen complementarity determining regions (CDRs). Genetically reproducible or ‘public’ antibodies can arise when the encoded CDRs play deterministic roles in antigen recognition, notably within human broad...

Full description

Bibliographic Details
Main Authors: Larance Ronsard, Ashraf S. Yousif, Julianne Peabody, Vintus Okonkwo, Pascal Devant, Alemu Tekewe Mogus, Ralston M. Barnes, Daniel Rohrer, Nils Lonberg, David Peabody, Bryce Chackerian, Daniel Lingwood
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
antibody
B cell receptor
lineage
VLP
prime
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.730471/full

Similar Items

Similar Items