Improved synthesis of SV2A targeting radiotracer [11C]UCB-J

Improved synthesis of SV2A targeting radiotracer [11C]UCB-J

Abstract Introduction [11C]UCB-J is a tracer developed for PET (positron emission tomography) that has high affinity towards synaptic vesicle glycoprotein 2A (SV2A), a protein believed to participate in the regulation of neurotransmitter release in neurons and endocrine cells. The localisation of SV...

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Bibliographic Details
Main Authors: Johanna Rokka, Eva Schlein, Jonas Eriksson
Format: Article
Language:English
Published: SpringerOpen 2019-11-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
[11C]UCB-J
SVA2
Synaptic density
PET
Synaptic vesicle glycoprotein
Suzuki-Miyaura coupling
Online Access:https://doi.org/10.1186/s41181-019-0080-5

Internet

https://doi.org/10.1186/s41181-019-0080-5

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