Oral Chronic Toxicity of the Safe Tetrodotoxin Dose Proposed by the European Food Safety Authority and Its Additive Effect with Saxitoxin

Oral Chronic Toxicity of the Safe Tetrodotoxin Dose Proposed by the European Food Safety Authority and Its Additive Effect with Saxitoxin

Tetrodotoxin (TTX) is a potent natural toxin causative of human food intoxications that shares its mechanism of action with the paralytic shellfish toxin saxitoxin (STX). Both toxins act as potent blockers of voltage-gated sodium channels. Although human intoxications by TTX were initially described...

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Bibliographic Details
Main Authors: Andrea Boente-Juncal, Paz Otero, Inés Rodríguez, Mercedes Camiña, Mercedes Rodriguez-Vieytes, Carmen Vale, Luis M. Botana
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Toxins
Subjects:
Tetrodotoxin
saxitoxin
risk assessment
oral chronic toxicity
mollusk.
Online Access:https://www.mdpi.com/2072-6651/12/5/312

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