Analysis of drug binding pockets and repurposing opportunities for twelve essential enzymes of ESKAPE pathogens

Background The rapid increase in antibiotic resistance by various bacterial pathogens underlies the significance of developing new therapies and exploring different drug targets. A fraction of bacterial pathogens abbreviated as ESKAPE by the European Center for Disease Prevention and Control have be...

Full description

Bibliographic Details
Main Authors: Sadia Naz, Tony Ngo, Umar Farooq, Ruben Abagyan
Format: Article
Language:English
Published: PeerJ Inc. 2017-09-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/3765.pdf