<it>N</it>-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor
<p>Abstract</p> <p>Background</p> <p>Microglia provide continuous immune surveillance of the CNS and upon activation rapidly change phenotype to express receptors that respond to chemoattractants during CNS damage or infection. These activated microglia undergo directed...
Main Authors: | Vogel Zvi, Juknat Ana, Rimmerman Neta, Hu Sherry SJ, McHugh Douglas, Walker J Michael, Bradshaw Heather B |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2010-03-01
|
Series: | BMC Neuroscience |
Online Access: | http://www.biomedcentral.com/1471-2202/11/44 |
Similar Items
-
GPR18 undergoes a high degree of constitutive trafficking but is unresponsive to N-Arachidonoyl Glycine
by: David B. Finlay, et al.
Published: (2016-03-01) -
Delta 9-THC and N-arachidonoyl glycine regulate BV-2 microglial morphology and cytokine release plasticity: implications for signaling at GPR18
by: Douglas eMcHugh, et al.
Published: (2014-01-01) -
Modulation of Astrocyte Activity by Cannabidiol, a Nonpsychoactive Cannabinoid
by: Ewa Kozela, et al.
Published: (2017-07-01) -
Protective Effect of N-Arachidonoyl Glycine-GPR18 Signaling after Excitotoxical Lesion in Murine Organotypic Hippocampal Slice Cultures
by: Urszula Grabiec, et al.
Published: (2019-03-01) -
Neuroprotective and cerebrovascular effects of endogenous N-Arachidonoyl-GABA and its putative Cox-2 metabolite – GABA conjugate with Prostaglandin E2
by: Narine R. Mirzoyan, et al.
Published: (2021-09-01)