Integrative Analysis of Transcriptome-Wide Association Study and mRNA Expression Profiles Identified Candidate Genes and Pathways Associated With Acute Myocardial Infarction

Integrative Analysis of Transcriptome-Wide Association Study and mRNA Expression Profiles Identified Candidate Genes and Pathways Associated With Acute Myocardial Infarction

BackgroundAcute myocardial infarction (AMI), characterized by an event of myocardial necrosis, is a common cardiac emergency worldwide. However, the genetic mechanisms of AMI remain largely elusive.MethodsA genome-wide association study dataset of AMI was obtained from the CARDIoGRAMplusC4D project....

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Bibliographic Details
Main Authors: Guanzhong Chen, Liwei Liu, Huanqiang Li, Zhubin Lun, Ziling Mai, Wenguang Lai, Enzhao Chen, Chunyun Zhou, Sijia Yu, Junqing Yang, Shiqun Chen, Jiyan Chen, Yong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Genetics
Subjects:
acute myocardial infarction
transcriptome-wide association study
genome-wide association study
mRNA expression profiles
biological process
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.616492/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.616492/full

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