Could α-Synuclein Amyloid-Like Aggregates Trigger a Prionic Neuronal Invasion?
Parkinson’s disease (PD), a progressive neurodegenerative disease primarily affecting voluntary and controlled movement, is characterized by abnormal accumulations of α-synuclein (α-syn) in intraneuronal Lewy bodies. In the last years, the increased number of evidences from both the in vitro and in...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2015-01-01
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Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2015/172018 |