Neurobiological Mechanisms of Pelvic Pain

Neurobiological Mechanisms of Pelvic Pain

Pelvic pain is a common condition which significantly deteriorates health-related quality of life. The most commonly identified causes of pain in the pelvic region are gynaecologic, urologic, gastrointestinal, neurological, and musculoskeletal. However, in up to 33% of patients the source of this sy...

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Main Authors: Massimo Origoni, Umberto Leone Roberti Maggiore, Stefano Salvatore, Massimo Candiani
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/903848
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spelling doaj-c49c4ed18cea45c19090ed760a2539a32020-11-24T23:46:03ZengHindawi LimitedBioMed Research International2314-61332314-61412014-01-01201410.1155/2014/903848903848Neurobiological Mechanisms of Pelvic PainMassimo Origoni0Umberto Leone Roberti Maggiore1Stefano Salvatore2Massimo Candiani3Obstetrics and Gynecology Unit, Vita-Salute San Raffaele University and IRCCS San Raffaele Hospital, Via Olgettina 58-60, 20132 Milan, ItalyObstetrics and Gynecology Unit, Vita-Salute San Raffaele University and IRCCS San Raffaele Hospital, Via Olgettina 58-60, 20132 Milan, ItalyObstetrics and Gynecology Unit, Vita-Salute San Raffaele University and IRCCS San Raffaele Hospital, Via Olgettina 58-60, 20132 Milan, ItalyObstetrics and Gynecology Unit, Vita-Salute San Raffaele University and IRCCS San Raffaele Hospital, Via Olgettina 58-60, 20132 Milan, ItalyPelvic pain is a common condition which significantly deteriorates health-related quality of life. The most commonly identified causes of pain in the pelvic region are gynaecologic, urologic, gastrointestinal, neurological, and musculoskeletal. However, in up to 33% of patients the source of this symptom is not identified, frustrating both patients and health-care professionals. Pelvic pain may involve both the somatic and visceral systems, making the differential diagnosing challenging. This paper aimed to review the mechanisms involved in pelvic pain perception by analyzing the neural plasticity and molecules which are involved in these complex circuits.http://dx.doi.org/10.1155/2014/903848
collection DOAJ
language English
format Article
sources DOAJ
author Massimo Origoni
Umberto Leone Roberti Maggiore
Stefano Salvatore
Massimo Candiani
spellingShingle Massimo Origoni
Umberto Leone Roberti Maggiore
Stefano Salvatore
Massimo Candiani
Neurobiological Mechanisms of Pelvic Pain
BioMed Research International
author_facet Massimo Origoni
Umberto Leone Roberti Maggiore
Stefano Salvatore
Massimo Candiani
author_sort Massimo Origoni
title Neurobiological Mechanisms of Pelvic Pain
title_short Neurobiological Mechanisms of Pelvic Pain
title_full Neurobiological Mechanisms of Pelvic Pain
title_fullStr Neurobiological Mechanisms of Pelvic Pain
title_full_unstemmed Neurobiological Mechanisms of Pelvic Pain
title_sort neurobiological mechanisms of pelvic pain
publisher Hindawi Limited
series BioMed Research International
issn 2314-6133
2314-6141
publishDate 2014-01-01
description Pelvic pain is a common condition which significantly deteriorates health-related quality of life. The most commonly identified causes of pain in the pelvic region are gynaecologic, urologic, gastrointestinal, neurological, and musculoskeletal. However, in up to 33% of patients the source of this symptom is not identified, frustrating both patients and health-care professionals. Pelvic pain may involve both the somatic and visceral systems, making the differential diagnosing challenging. This paper aimed to review the mechanisms involved in pelvic pain perception by analyzing the neural plasticity and molecules which are involved in these complex circuits.
url http://dx.doi.org/10.1155/2014/903848
work_keys_str_mv AT massimoorigoni neurobiologicalmechanismsofpelvicpain
AT umbertoleonerobertimaggiore neurobiologicalmechanismsofpelvicpain
AT stefanosalvatore neurobiologicalmechanismsofpelvicpain
AT massimocandiani neurobiologicalmechanismsofpelvicpain
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