Hypertonic saline increases lung epithelial lining fluid glutathione and thiocyanate: two protective CFTR-dependent thiols against oxidative injury

<p>Abstract</p> <p>Background</p> <p>Cystic fibrosis is a debilitating lung disease due to mutations in the cystic fibrosis transmembrane conductance regulator protein (CFTR) and is associated with chronic infections resulting in elevated myeloperoxidase activity and ge...

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Bibliographic Details
Main Authors: Gould Neal S, Gauthier Steve, Kariya Chirag T, Min Elysia, Huang Jie, Brian Day J
Format: Article
Language:English
Published: BMC 2010-08-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/11/1/119