Mandibular Metastasis of Thyroid Carcinoma: A Case Report
Metastatic carcinomas to the jaw bones are uncommon and comprise to about 1% of all malignant oral neoplasms. It may be the first indication of an unknown malignancy from a distant primary site which is usually associated with poor prognosis. We report a rare case of thyroid carcinoma metastatic t...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2014-07-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/4588/9079_CE(Ra)_F(Sh)_PF1(PAK)_PFA(AK)_PF2(AGAK)_PF2(PN).pdf |
| Summary: | Metastatic carcinomas to the jaw bones are uncommon and comprise to about 1% of all malignant oral neoplasms. It may be the first
indication of an unknown malignancy from a distant primary site which is usually associated with poor prognosis. We report a rare case
of thyroid carcinoma metastatic to the mandible in a 76-year-old elderly male patient in which the lesion was asymptomatic. Microscopic
examination revealed a tumour structure consisting of cords and islands of infiltrating epithelium. The immunohistochemical marker,
thyroid transcription factor -1 was done which showed a positive staining by the follicular cells. The tumour was diagnosed as metastatic
follicular thyroid carcinoma. It should be emphasized that histopathological diagnosis along with panel of markers play an important role
in diagnosing the site of origin of bone metastasis and these lesions should be included in the differential diagnosis of asymptomatic
jaw lesions. |
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| ISSN: | 2249-782X 0973-709X |