Enterocyte shedding and epithelial lining repair following ischemia of the human small intestine attenuate inflammation.

BACKGROUND: Recently, we observed that small-intestinal ischemia and reperfusion was found to entail a rapid loss of apoptotic and necrotic cells. This study was conducted to investigate whether the observed shedding of ischemically damaged epithelial cells affects IR induced inflammation in the hum...

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Bibliographic Details
Main Authors: Robert A Matthijsen, Joep P M Derikx, Dian Kuipers, Ronald M van Dam, Cornelis H C Dejong, Wim A Buurman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2737143?pdf=render