The evaluation of the reverse algorithm for syphilis screening in blood donors

The evaluation of the reverse algorithm for syphilis screening in blood donors

Background: In Turkey, prior to transfusion and apheresis, it is mandatory to screen blood for HBsAg, anti-HCV, anti-HIV 1/2, and syphilis. In recent years, efforts have been made to create effective diagnostic algorithms for screening, and as a screening strategy, many countries have switched from...

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Bibliographic Details
Main Authors: Berkem Rukiye, Karakoç Ayşe Esra
Format: Article
Language:English
Published: Sciendo 2019-10-01
Series:Romanian Journal of Laboratory Medicine
Subjects:
blood donors
syphilis screening tests
confirmation
reverse algorithm
Online Access:https://doi.org/10.2478/rrlm-2019-0039
id doaj-c4850b8d78774711aa248aa1c6f8de8e
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spelling doaj-c4850b8d78774711aa248aa1c6f8de8e2021-09-05T14:01:31ZengSciendoRomanian Journal of Laboratory Medicine2284-56232019-10-0127438338810.2478/rrlm-2019-0039rrlm-2019-0039The evaluation of the reverse algorithm for syphilis screening in blood donorsBerkem Rukiye0Karakoç Ayşe Esra1Ankara Education and Research Hospital, TurkeyAnkara Education and Research Hospital, TurkeyBackground: In Turkey, prior to transfusion and apheresis, it is mandatory to screen blood for HBsAg, anti-HCV, anti-HIV 1/2, and syphilis. In recent years, efforts have been made to create effective diagnostic algorithms for screening, and as a screening strategy, many countries have switched from traditional algorithms to reverse algorithms. This study was carried out to evaluate the results we obtained after changing to chemiluminescence immunoassay (CLIA) based reverse algorithm, which is more sensitive and specific than the traditional algorithm and VDRL test we currently use for syphilis screening.https://doi.org/10.2478/rrlm-2019-0039blood donorssyphilis screening testsconfirmationreverse algorithm
collection DOAJ
language English
format Article
sources DOAJ
author Berkem Rukiye
Karakoç Ayşe Esra
spellingShingle Berkem Rukiye
Karakoç Ayşe Esra
The evaluation of the reverse algorithm for syphilis screening in blood donors
Romanian Journal of Laboratory Medicine
blood donors
syphilis screening tests
confirmation
reverse algorithm
author_facet Berkem Rukiye
Karakoç Ayşe Esra
author_sort Berkem Rukiye
title The evaluation of the reverse algorithm for syphilis screening in blood donors
title_short The evaluation of the reverse algorithm for syphilis screening in blood donors
title_full The evaluation of the reverse algorithm for syphilis screening in blood donors
title_fullStr The evaluation of the reverse algorithm for syphilis screening in blood donors
title_full_unstemmed The evaluation of the reverse algorithm for syphilis screening in blood donors
title_sort evaluation of the reverse algorithm for syphilis screening in blood donors
publisher Sciendo
series Romanian Journal of Laboratory Medicine
issn 2284-5623
publishDate 2019-10-01
description Background: In Turkey, prior to transfusion and apheresis, it is mandatory to screen blood for HBsAg, anti-HCV, anti-HIV 1/2, and syphilis. In recent years, efforts have been made to create effective diagnostic algorithms for screening, and as a screening strategy, many countries have switched from traditional algorithms to reverse algorithms. This study was carried out to evaluate the results we obtained after changing to chemiluminescence immunoassay (CLIA) based reverse algorithm, which is more sensitive and specific than the traditional algorithm and VDRL test we currently use for syphilis screening.
topic blood donors
syphilis screening tests
confirmation
reverse algorithm
url https://doi.org/10.2478/rrlm-2019-0039
work_keys_str_mv AT berkemrukiye theevaluationofthereversealgorithmforsyphilisscreeninginblooddonors
AT karakocayseesra theevaluationofthereversealgorithmforsyphilisscreeninginblooddonors
AT berkemrukiye evaluationofthereversealgorithmforsyphilisscreeninginblooddonors
AT karakocayseesra evaluationofthereversealgorithmforsyphilisscreeninginblooddonors
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