Splenectomy in a patient with treatment-resistant visceral leishmaniasis: a case report

Visceral leishmaniasis (VL), also known as Kala-azar, is a systemic infection caused by a protozoan (Leishmania) and, in its classic form, is a serious illness associated with malnutrition, anemia, hepatosplenomegaly, infectious processes and coagulopathies. The effect of splenectomy in patients wit...

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Bibliographic Details
Main Authors: Robson Azevedo Dutra, Laura Ferreira Dutra, Milene de Oliveira Reis, Raul Coelho Lambert
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2012-02-01
Series:Revista da Sociedade Brasileira de Medicina Tropical
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822012000100027&lng=en&tlng=en
Description
Summary:Visceral leishmaniasis (VL), also known as Kala-azar, is a systemic infection caused by a protozoan (Leishmania) and, in its classic form, is a serious illness associated with malnutrition, anemia, hepatosplenomegaly, infectious processes and coagulopathies. The effect of splenectomy in patients with visceral leishmaniasis is not well defined; however, it is known that the spleen is the largest reservoir of infected cells belonging to the reticulo endothelial system. Therefore, the surgical procedure is an option for the debulking of parasites, providing a cure for refractory VL and minimizing the complications of hypersplenism.
ISSN:1678-9849