11C-PK11195 plasma metabolization has the same rate in multiple sclerosis patients and healthy controls: a cross-sectional study

11C-PK11195 plasma metabolization has the same rate in multiple sclerosis patients and healthy controls: a cross-sectional study

11C-PK11195 is a positron emitter tracer used for Positron Emission Tomography (PET) imaging of innate immune cell activation in studies of neuroinflammatory diseases. For the image quantitative analysis, it is necessary to quantify the intact fraction of this tracer in the arterial plasma during im...

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Bibliographic Details
Main Authors: Aline Morais de Souza, Milena Sales Pitombeira, Larissa Estessi de Souza, Fabio Luiz Navarro Marques, Carlos Alberto Buchpiguel, Caroline Cristiano Real, Daniele de Paula Faria
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Neural Regeneration Research
Subjects:
11c-pk11195; hplc; kinetic modeling; metabolization; multiple sclerosis; neuroinflammation; pet imaging; pet tracer; radiometabolites
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=12;spage=2494;epage=2498;aulast=de

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