Soluble CEACAM8 interacts with CEACAM1 inhibiting TLR2-triggered immune responses.

Soluble CEACAM8 interacts with CEACAM1 inhibiting TLR2-triggered immune responses.

Lower respiratory tract bacterial infections are characterized by neutrophilic inflammation in the airways. The carcinoembryonic antigen-related cell adhesion molecule (CEACAM) 8 is expressed in and released by human granulocytes. Our study demonstrates that human granulocytes release CEACAM8 in res...

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Bibliographic Details
Main Authors: Bernhard B Singer, Lena Opp, Annina Heinrich, Frauke Schreiber, Ramona Binding-Liermann, Luis Carlos Berrocal-Almanza, Kerstin A Heyl, Mario M Müller, Andreas Weimann, Janine Zweigner, Hortense Slevogt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3990526?pdf=render

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http://europepmc.org/articles/PMC3990526?pdf=render

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