Dynamic Changes in Quantitative Features of Human Gastric Lesions

Quantitative DNA, morphometric cellular and nuclear variables were evaluated in surgical biopsies from patients with various gastric lesions: chronic gastritis, chronic ulcers, adenomatous polyps (gastric adenomas), primary carcinomas and their corresponding lymph‐node metastases. Paraffin‐embedded...

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Bibliographic Details
Main Authors: Ventzeslav Enchev, Jean Paul Rigaut
Format: Article
Language:English
Published: Hindawi Limited 1997-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.1155/1997/942371
Description
Summary:Quantitative DNA, morphometric cellular and nuclear variables were evaluated in surgical biopsies from patients with various gastric lesions: chronic gastritis, chronic ulcers, adenomatous polyps (gastric adenomas), primary carcinomas and their corresponding lymph‐node metastases. Paraffin‐embedded tissue sections were studied by static cytophotometry (plug method), karyometry (measurements with a graduated eyepiece micrometer of the major and minor axes of the elliptic nuclear profiles, and calculation of profile areas), and measurements of cellular profiles (largest and smallest caliper diameters). Tissue lymphocytes from the same slide were used as diploid controls for the DNA evaluations.
ISSN:0921-8912
1878-3651