The Immune Phenotype of Isolated Lymphoid Structures in Non-Tumorous Colon Mucosa Encrypts the Information on Pathobiology of Metastatic Colorectal Cancer

The Immune Phenotype of Isolated Lymphoid Structures in Non-Tumorous Colon Mucosa Encrypts the Information on Pathobiology of Metastatic Colorectal Cancer

The gut-associated lymphoid tissue represents an integral part of the immune system. Among the powerful players of the mucosa-associated lymphoid tissue are isolated lymphoid structures (ILSs), which as information centers, drive the local (and systemic) adaptive immune responses. Germinal center re...

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Bibliographic Details
Main Authors: Felicitas Mungenast, Anastasia Meshcheryakova, Andrea Beer, Martina Salzmann, Dietmar Tamandl, Thomas Gruenberger, Peter Pietschmann, Oskar Koperek, Peter Birner, Ilan Kirsch, Harlan Robins, Martina Mittlboeck, Markus Jaritz, Michael Bergmann, Philip Zimmermann, Diana Mechtcheriakova
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cancers
Subjects:
lymphoid structures
colonic mucosa
metastatic colorectal cancer
immuno-oncology
B lymphocytes
germinal center
Online Access:https://www.mdpi.com/2072-6694/12/11/3117

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