HERV-K Gag RNA and Protein Levels Are Elevated in Malignant Regions of the Prostate in Males with Prostate Cancer
Heightened expression of human endogenous retrovirus (HERV) sequences has been associated with a range of malignancies, including prostate cancer, suggesting that they may serve as useful diagnostic or prognostic cancer biomarkers. We analysed the expression of HERV-K (Gag and Env/Np9 regions), HERV...
Main Authors: | Simin D. Rezaei, Joshua A. Hayward, Sam Norden, John Pedersen, John Mills, Anna C. Hearps, Gilda Tachedjian |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-03-01
|
Series: | Viruses |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4915/13/3/449 |
Similar Items
-
Comprehensive Analysis of HERV Transcriptome in HIV+ Cells: Absence of HML2 Activation and General Downregulation of Individual HERV Loci
by: Nicole Grandi, et al.
Published: (2020-04-01) -
HERVs New Role in Cancer: From Accused Perpetrators to Cheerful Protectors
by: Norbert Bannert, et al.
Published: (2018-02-01) -
HERV-K(HML7) Integrations in the Human Genome: Comprehensive Characterization and Comparative Analysis in Non-Human Primates
by: Nicole Grandi, et al.
Published: (2021-05-01) -
Detection of Human Endogenous Retrovirus K (HERV-K) transcripts in human prostate cancer cell lines
by: Lorenzo eAgoni, et al.
Published: (2013-07-01) -
HERV-K(HML-2), the best preserved family of HERVs: endogenisation, expression and implications in health and disease
by: Oliver eHohn, et al.
Published: (2013-09-01)