IL-4 induced MUC4 enhancement in respiratory epithelial cells <it>in vitro </it>is mediated through JAK-3 selective signaling

<p>Abstract</p> <p>Background</p> <p>Recent studies have identified MUC4 mucin as a ligand for activation of ErbB2, a receptor tyrosine kinase that modulates epithelial cell proliferation following epithelial damage in airways of asthmatics. In this study, we investigat...

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Bibliographic Details
Main Authors: Sachdev Goverdhan P, Xia Baoyun, Damera Gautam
Format: Article
Language:English
Published: BMC 2006-03-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/7/1/39