MeCP2 regulates gene expression through recognition of H3K27me3

MeCP2 is a transcriptional repressor and associates with nucleosomes. Here the authors show interaction of MeCP2 and H3K27me3 by biochemical assay and chromatin immunoprecipitation sequencing analysis.

Bibliographic Details
Main Authors: Wooje Lee, Jeeho Kim, Jung-Mi Yun, Takbum Ohn, Qizhi Gong
Format: Article
Language:English
Published: Nature Publishing Group 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16907-0