Rapid statistical discrimination of fluorescence images of T cell receptors on immobilizing surfaces with different coating conditions

Abstract The spatial organization of T cell receptors (TCRs) correlates with membrane-associated signal amplification, dispersion, and regulation during T cell activation. Despite its potential clinical importance, quantitative analysis of the spatial arrangement of TCRs from standard fluorescence i...

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Bibliographic Details
Main Authors: Badeia Saed, Rangika Munaweera, Jesse Anderson, William D. O’Neill, Ying S. Hu
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-94730-3