Systems pharmacology of adiposity reveals inhibition of EP300 as a common therapeutic mechanism of caloric restriction and resveratrol for obesity

Systems pharmacology of adiposity reveals inhibition of EP300 as a common therapeutic mechanism of caloric restriction and resveratrol for obesity

Both caloric restriction and resveratrol have beneficial effects on obesity. However, the biochemical pathways that mediate these beneficial effects might be complex and interconnected and have not been fully elucidated. To reveal the common therapeutic mechanism of caloric restriction and resveratr...

Full description

Bibliographic Details
Main Authors: Yuhei eNishimura, Shota eSasagawa, Michiko eAriyoshi, Sayuri eIchikawa, Yasuhito eShimada, Koki eKawaguchi, Reiko eKawase, Reiko eYamamoto, Takuma eUehara, Takaaki eYanai, Ryoji eTakata, Toshio eTanaka
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Pharmacology
Subjects:
Adipose Tissue
Caloric Restriction
Obesity
Zebrafish
resveratrol
Systems Pharmacology
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00199/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00199/full

Similar Items