KIM-1 Mediates High Glucose-Induced Autophagy and Apoptosis in Renal Tubular Epithelial Cells

KIM-1 Mediates High Glucose-Induced Autophagy and Apoptosis in Renal Tubular Epithelial Cells

Background/Aim: To investigate the role of kidney injury molecular 1 (KIM-1) in high glucose-induced autophagy and apoptosis in renal tubular epithelial cells. Methods: Human renal tubular epithelial cells (HK2) were treated with normal glucose (NG, D -glucose 5.6 mmol/L), high glucose (HG, 30 mmol/...

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Bibliographic Details
Main Authors: Rong Gou, Juntong Chen, Shifeng Sheng, Ruiqiang Wang, Yudong Fang, Zijun Yang, Liuwei Wang, Lin Tang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-06-01
Series:Cellular Physiology and Biochemistry
Subjects:
LC3II
Diabetic nephropathy
Autophagosome
Renal fibrosis
Online Access:http://www.karger.com/Article/FullText/445598

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