FceRI density and spontaneous secretion from human basophils.
Mast cells and basophils depend on aggregation of the high-affinity IgE receptor, FceRI, to initiate secretion. A variety of studies have shown that FceRI densities vary 100 fold among subjects' basophils and it has been speculated that high densities might be responsible for unusual behaviors...
Main Author: | Donald MacGlashan |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5495218?pdf=render |
Similar Items
-
The relationship between released soluble FceRI-alpha and its cell surface density on human basophils.
by: Donald MacGlashan
Published: (2021-01-01) -
Molekulární mechanismy regulace FcɛRI signalizace žírných buněk
by: Bambousková, Monika
Published: (2016) -
Expression profiling of human basophils: modulation by cytokines and secretagogues.
by: Donald MacGlashan
Published: (2015-01-01) -
A spatio-temporal model reveals self-limiting FcɛRI cross-linking by multivalent antigens
by: Md Shahinuzzaman, et al.
Published: (2018-01-01) -
A TNFRSF14-FcɛRI-mast cell pathway contributes to development of multiple features of asthma pathology in mice
by: Riccardo Sibilano, et al.
Published: (2016-12-01)