Proteasome Inhibitors: Harnessing Proteostasis to Combat Disease

The proteasome is the central component of the main cellular protein degradation pathway. During the past four decades, the critical function of the proteasome in numerous physiological processes has been revealed, and proteasome activity has been linked to various human diseases. The proteasome pre...

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Bibliographic Details
Main Authors: David J. Sherman, Jing Li
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Molecules
Subjects:
p97
Online Access:https://www.mdpi.com/1420-3049/25/3/671