Microbiota: the missing link in the etiology of inflammatory bowel disease

• Main Authors: Micu Ioan Sergiu, Manea Madalina Elena, Musat Marilena, Dumitru Andrada, Popoiag Roxana Emanuela
• Format: Article
• Language: English
• Published: Ion Motofei, Carol Davila University 2020-04-01
• Series: Journal of Mind and Medical Sciences
• Subjects: the microbiota; dysbiosis; inflammatory bowel disease; crohn’s disease; ulceratice colitis.
• Online Access: https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1219&context=jmms

Within its twisted and tight walls, where a hostile and arid environment prevails, the lumen of the digestive tract nests a true microuniverse called the microbiota. The existing relationship between humans and these microorganisms is one in which both benefit, creating a condition called Eubiosis. The dynamic relationship existing between the microbiota and the human body can be affected at various times, leading to an imbalance that may have important implications on health and generating a condition called Disbiosis. Recent studies have highlighted possible links between several diseases with incompletely elucidated etiology and disturbances of the microbiota. In this review we aim to analyze the existing relationship between the imbalances of the gastrointestinal flora and the etiopathogeny inflammatory bowel diseases, a group of diseases whose incidence has increased considerably in recent years.