Exploring cell membrane water exchange in aquaporin-4-deficient ischemic mouse brain using diffusion-weighted MRI

Exploring cell membrane water exchange in aquaporin-4-deficient ischemic mouse brain using diffusion-weighted MRI

Abstract Background Aquaporin-4 is a membrane channel protein that is highly expressed in brain astrocytes and facilitates the transport of water molecules. It has been suggested that suppression of aquaporin-4 function may be an effective treatment for reducing cellular edema after cerebral infarct...

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Bibliographic Details
Main Authors: Takuya Urushihata, Hiroyuki Takuwa, Manami Takahashi, Jeff Kershaw, Yasuhiko Tachibana, Nobuhiro Nitta, Sayaka Shibata, Masato Yasui, Makoto Higuchi, Takayuki Obata
Format: Article
Language:English
Published: SpringerOpen 2021-10-01
Series:European Radiology Experimental
Subjects:
Aquaporin 4
Cell membrane
Cerebral infarction
Diffusion magnetic resonance imaging
Experimental animal models
Online Access:https://doi.org/10.1186/s41747-021-00244-y

Internet

https://doi.org/10.1186/s41747-021-00244-y

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