Evaluation of lentinan effects on cytochrome P450 activity in rats by a cocktail method
Objective(s): In this study, a cocktail of probe drugs was used to assess whether lentinan could influence the activities of rat enzymes CYP3A4, CYP2D6, CYP1A2, CYP2C19, and CYP2C9 in vivo. Materials and Methods: Fourteen days after intraperitoneal injection of lentinan, rats were given an oral dose...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Mashhad University of Medical Sciences
2019-03-01
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Series: | Iranian Journal of Basic Medical Sciences |
Subjects: | |
Online Access: | http://ijbms.mums.ac.ir/article_12194_e36ea5b976a2f89ce7525a89090adc1e.pdf |