Safety Assessment of Ubiquinol Acetate: Subchronic Toxicity and Genotoxicity Studies

Coenzyme Q10 (CoQ10) is a lipid soluble, endogenous antioxidant present at highest levels in the heart followed by the kidney and liver. The reduced CoQ10 ubiquinol is well known for its chemical instability and low bioavailability. The present study was designed to synthesize ubiquinol acetate, whi...

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Bibliographic Details
Main Authors: Gajanan Deshmukh, Suresh B. Venkataramaiah, Chandrashekar M. Doreswamy, Mohan C. Umesh, Rajesh B. Subbanna, Bikram K. Pradhan, Srinivas Seekallu, Rajan Sekar, Karthick Prabhu, Sathish Sadagopan, Shri Natrajan Arumugam, Satish Sharma, Govindarajulu Gavara, Selvakumar Balaraman, Ganesh Sambasivam, Ravindra K. Chandrappa, Sarah Flynn, Prasad Shivarudraiah
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Journal of Toxicology
Online Access:http://dx.doi.org/10.1155/2019/3680757