The Integration Preference of Sleeping Beauty at Non-TA Site Is Related to the Transposon End Sequences
Recently, we proved that Sleeping Beauty (SB) transposon integrates into non-TA sites at a lower frequency. Here, we performed a further study on the non-TA integration of SB and showed that (1) SB can integrate into non-TA sites in HEK293T cells as well as in mouse cell lines; (2) Both the hyperact...
Main Authors: | Yiting Zhou, Guangwei Ma, Jiawen Yang, Zenghong Gao, Yabin Guo |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-03-01
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Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fgene.2021.639125/full |
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