(R)-(−)-2-[(5-Oxido-5-phenyl-5λ4-isoquino[4,3-c][2,1]benzothiazin-12-yl)amino]benzonitrile

(R)-(−)-2-[(5-Oxido-5-phenyl-5λ4-isoquino[4,3-c][2,1]benzothiazin-12-yl)amino]benzonitrile

Copper-catalyzed cross-coupling between (S)-S-methyl-S-phenylsulfoximine (1) and 2-iodobenzonitrile (2) resulted in the discovery of an unprecedented one-pot triple arylation sequence to give (R)-(−)-2-[(5-oxido-5-phenyl-5λ4-isoquino[4,3-c][2,1]benzothiazin- 12-yl)amino]benzonitrile (4). Here, we de...

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Bibliographic Details
Main Authors: Marcus Frings, Iuliana Atodiresei, Carsten Bolm
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:Molbank
Subjects:
sulfoximines
benzothiazines
arylation
copper catalysis
Online Access:http://www.mdpi.com/1422-8599/2014/3/M834

Internet

http://www.mdpi.com/1422-8599/2014/3/M834

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